| Games for Wednesday, February 21, 2018 | ||||||
| Visitor | Home | Time (ET) | ||||
| - | Barry | 78 | - | Lynn | 60 | F |
| - | Bemidji State | 72 | - | Augustana | 88 | F |
| - | Bloomfield | 89 | - | Felician | 81 | F |
| - | Bloomsburg | 74 | - | Mansfield | 73 | F |
| - | Caldwell | 83 | - | Post | 51 | F |
| - | Carson-Newman | 77 | #1 | Lincoln Memorial | 89 | F |
| - | Central State | 101 | - | Salem International | 99 | F/OT |
| - | Chestnut Hill | 69 | - | Holy Family | 75 | F |
| - | Cheyney | 84 | - | Lock Haven | 87 | F/OT |
| - | Clarion | 68 | - | Gannon | 84 | F |
| - | Coker | 82 | - | Wingate | 93 | F |
| - | Columbus State | 90 | - | Flagler | 87 | F |
| - | Concord | 95 | - | West Virginia State | 91 | F |
| - | Concordia (N.Y.) | 60 | - | Dominican (N.Y.) | 51 | F |
| - | Concordia-St. Paul | 52 | #11 | Northern State | 80 | F |
| - | East Stroudsburg | 102 | - | Kutztown | 91 | F |
| - | Edinboro | 69 | - | Indiana (Pa.) | 77 | F |
| - | Embry-Riddle | 86 | - | Florida Tech | 79 | F/OT |
| - | Emmanuel | 80 | - | King | 93 | F |
| - | Fairmont State | 71 | - | West Virginia Wesleyan | 68 | F |
| - | Fayetteville State | 75 | - | Shaw | 85 | F |
| - | Francis Marion | 60 | - | UNC Pembroke | 66 | F |
| - | Georgia College | 69 | - | Young Harris | 85 | F |
| - | Georgia Southwestern | 61 | - | Clayton State | 63 | F |
| - | Lane | 78 | - | Spring Hill | 82 | F |
| - | Lincoln (Pa.) | 87 | - | Chowan | 81 | F/OT |
| - | Livingstone | 64 | - | St. Augustine's | 57 | F |
| - | Minnesota Crookston | 68 | - | Sioux Falls | 98 | F |
| - | Minnesota Duluth | 89 | - | Winona State | 77 | F/OT |
| - | Molloy | 73 | #17 | Bridgeport | 83 | F |
| - | MSU Moorhead | 79 | - | Minnesota State | 82 | F |
| - | Newberry | 92 | - | Catawba | 84 | F |
| - | Newman | 68 | - | Rogers State | 65 | F |
| - | North Georgia | 103 | - | Lander | 92 | F |
| - | Oakland City | 92 | - | Baptist Bible | 56 | F |
| - | Palm Beach Atlantic | 97 | - | Nova Southeastern | 92 | F/OT |
| - | Pittsburgh-Johnstown | 71 | - | Mercyhurst | 64 | F |
| #2 | Queens (N.C.) | 75 | - | Lenoir-Rhyne | 55 | F |
| - | Queens (N.Y.) | 86 | - | Mercy | 76 | F |
| - | Saint Leo | 69 | - | Eckerd | 84 | F |
| - | St. Mary's | 67 | #24 | Dallas Baptist | 88 | F |
| - | Seton Hill | 84 | - | California (Pa.) | 64 | F |
| - | Shepherd | 65 | - | Glenville State | 72 | F |
| - | Shippensburg | 59 | - | West Chester | 78 | F |
| - | Tampa | 56 | - | Florida Southern | 75 | F |
| - | Texas A&M International | 63 | - | St. Edward's | 77 | F |
| - | Thomas Jefferson | 65 | - | Goldey Beacom | 76 | F |
| - | Tusculum | 64 | - | Anderson | 81 | F |
| - | U-Mary | 73 | - | Southwest Minnesota State | 78 | F |
| - | Upper Iowa | 71 | - | Minot State | 91 | F |
| - | USC Aiken | 75 | - | Augusta | 80 | F |
| - | UVa-Wise | 63 | - | Charleston | 73 | F |
| #16 | Virginia State | 75 | - | Bowie State | 65 | F |
| - | Virginia Union | 68 | - | Elizabeth City State | 72 | F |
| - | Wayne State (Neb.) | 57 | - | St. Cloud State | 81 | F |
| #5 | West Liberty | 112 | - | Notre Dame (Ohio) | 68 | F |
| #25 | Wheeling Jesuit | 90 | - | Urbana | 65 | F |
| - | Wilmington | 86 | - | Georgian Court | 74 | F |
| - | Winston-Salem State | 79 | - | Johnson C. Smith | 88 | F |
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